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Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome

Finnish Diabetes Association, Tampere, Finland

Markku Peltonen

Diabetes and Genetic Epidemiology Unit, National Public Health Institute Helsinki, Finland

Jaana Lindström

Diabetes and Genetic Epidemiology Unit, National Public Health Institute Helsinki, Finland

Liisa Saarikoski

Diabetes and Genetic Epidemiology Unit, National Public Health Institute Helsinki, Finland

Jouko Sundvall

Laboratory of Analytical Biochemistry, National Public Health Institute, Helsinki, Finland

Johan Gunnar Eriksson

Diabetes and Genetic Epidemiology Unit, National Public Health Institute Helsinki, Finland

Jaakko Tuomilehto

Department of Public Health, University of Helsinki, Helsinki, Finland

The aim of this study was to assess the performance of the Finnish Diabetes Risk Score as a screening tool for undetected type 2 diabetes (T2D), abnormal glucose tolerance (AGT) and metabolic syndrome in the general population.

In a cross-sectional, population-based survey, a total of 4, 622 subjects aged 45–74 years were invited to a health examination that included an oral glucose tolerance test. Full data with risk score estimate and glucose tolerance status were available for 2, 966 subjects without a prior history of diabetes.

The risk score was associated with the presence of previously undiagnosed T2D, AGT, metabolic syndrome and cardiovascular risk factors. The area under the receiver operating curve for the prevalence of undiagnosed diabetes was 0.72 in men and 0.73 in women. The sensitivity using a cutoff risk score of 11 to identify undiagnosed diabetes was 66% in men and 70% in women; the corresponding false-positive rates were 31% and 39%, respectively. The area under the receiver operating curve for detecting the metabolic syndrome was 0.72 in men and 0.75 in women.

The Finnish Diabetes Risk Score can be used as a self-administered test to screen subjects at high risk for T2D. It can also be used in the general population and clinical practice to identify undetected T2D, AGT and the metabolic syndrome.

Key Words: type 2 diabetes • glucose tolerance test • risk score • primary prevention • prevalence • screening

Diabetes and Vascular Disease Research, Vol. 2, No. 2, 67-72 (2005)
DOI: 10.3132/dvdr.2005.011


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